The REFLOW project aims to further develop circular and regenerative cities through the re-localisation of production and the re-configuration of material flows at different scales in cities. The project aims to include Fab Labs and makerspaces as catalysers of a systemic change in urban and peri-urban environments, which enable, visualize and regulate “four freedoms”: free movement of materials, people, (technological) knowledge, and commons, in order to reduce materials consumption, maximize multifunctional use of (public) spaces/building and envisage regenerative practices. New production and innovation spaces, such as Fab Labs, makerspaces, or innovations hubs are natural test-beds for local initiates to be incubated, nurtured, tested and scaled, allowing urban ecosystems to move towards green transition because they already operate as social experiments and portray examples of small-scale running economies.